Yes, you just have to find another way to detect if the Enter button is pressed. That can be done using HotKeySet. Here is the resulting code: #include <GuiConstantsEx.au3> #include <WindowsConstants.au3> #include <GuiComboBox.au3> #include <Misc.au3> ;Dim $sString = "Hello|world|AutoIt|rules|and|more|some|data" HotKeySet("{ENTER}", "EnterPressed") $hGUI = GUICreate("AutoComplete Combo Demo", 300, 200) $filelist = IniReadSection("files.ini", "files") Global $sString