I am using the following code in VBA to run Autoitcode.au3 file. Sub RunFileName() Dim runscript Dim FileName As String FileName = ThisWorkbook.Path & "\Autoitcode.au3" MsgBox (FileName) runscript = Shell("C:\Program Files (x86)\AutoIt3\AutoIt3_x64.exe " & FileName) End Sub The Autoit code I want to run, works fine when I directly run by double clicking the file in folder, but when I use this VBA code it gives me error of Autoit Line 0 Error ("File: E:\Data\Point") Error :