@Professor_Bernd  I got something running using the RegFree COM approach. At least is tested on my Win10 using VBScript and PowerShell This is how you can test it : 1. UNREGISTER the COM object first using regsvr32 /u AutoItX3_x64.dll 2. Create a MANIFEST file using this content, and save it using this EXACT name :  AutoItX3.sxs.manifest 3. Create a Test.vbs using this content : 4. Copy the 3 files to the C:\Temp folder : - AutoItX3_x64.dll - Auto