As someone said recently, StringRegExp... everywhere
#Include <Array.au3>
$sys_CONFQ = "POW:AC +2.000000E+01,+3,(@1)"
; change both space and comma in one shot
Msgbox(0,"", StringRegExpReplace($sys_CONFQ, '\s|,', "|"))
; or get the array directly, hey why not ?
$a = StringRegExp($sys_CONFQ, '[^\s,]+', 3)
_ArrayDisplay($a)