JLogan3o13,
I think I just figured it out. I needed to put in the sleep command while the exe extracts the file. After doing this it is now working. Thanks for the help. It's good to know there are folks willing to be patient and help out newbies like me. Thanks again.
#RequireAdmin
Run(@ScriptDir & '\VisionRMS 4.22.0 Client Install.exe')
AutoItSetOption('MouseCoordMode', 0) Sleep(10000)
WinWait('VisionRMS 4X - InstallShield Wizard')
WinActivate('VisionRMS 4X - InstallShield Wizard')
MouseClick('primary', 355, 362, 10, 0)