Maybe this trick was mentioned here. If so then I'm sorry...
This script allows to copy selected text (from SciTE-Lite and others) by middle click without keypress {Ctrl+C} or context menu.
#Include <Misc.au3>
GUICreate('', -1, -1, -1, -1, -1, 0x80)
While 1
Sleep(100)
If _IsPressed('04') Then
Send ("^c")
Sleep(10)
MsgBox(0, 'Clipboard text',ClipGet())
EndIf
WEnd
You can adapt it to make other jobs, i.e. to paste by middle click, to {Alt} open File line in IE or FireFox and so on.
Enjoy