File system watcher/monitor

[MISIIM 0]

What would be the best way to detect a change in a designated folder?

[sshrum 1]

mod times of files...might be a bit slow if the folder has a lot of files.

[MHz 73]

WMI does monitoring of files or directories. Here is an example here in VBS by the Scripting Guy. Translating to AutoIt is not too hard but it may not be exactly what you want. Should be enough to give you ideas and research some more.