After reading this page, (http://www.drububu.com/illustration/tsp/index.html) I was curious and I put together this script.
it is not a "stand alone" script, as it uses some third parties programs*, but in few steps it acomplish the conversion to the TSP art. The generated images are quite nice, but you have to try more attempts to find the right combinations of parameters for different source images. Best results can easily obtained with schematic black and wite images. Drag and drop for example something like in this link.
Also, set the "Variable thickness line" option and try with the image at this link for another example: (https://images.fineartamerica.com/images/artworkimages/mediumlarge/1/david-michelangelo-murphy-elliott.jpg)
Since used programs generate also some temporay files, please save this script and the dependencies into a single folder so to avoid the scattering of files around and also allowing the main script to find the needed programs.
Example of an TSP art generated with this script and related programs (the image on the left is converted in the image on the right) just drag and drop images on the GUI of the script and all is done automatically.

* Here are the links to download the needed "dependencies": ( just put all the stuff in a single folder along with the script.)
voronoi.exe http://www.drububu.com/illustration/tsp/voronoi.zip stippler.dll also contained in the above archive concorde.exe http://www.math.uwaterloo.ca/tsp/concorde/downloads/codes/cygwin/concorde.exe.gz this program needs the cygwin dll (a very nice one) (I've used 7zip to open this archive) cygwin1.dll https://cygwin.com/snapshots/ get one x86 cygwin1-xxxxxxxx.dll.xz (only dll) svg_extract.exe http://www.drububu.com/illustration/tsp/svg_extract.zip tsp2svg.exe http://www.drububu.com/illustration/tsp/tsp2svg.zip here the script:
; TSP Art generator #include <FileConstants.au3> #include <WinAPISys.au3> #include <GUIConstantsEx.au3> #include <WindowsConstants.au3> #include <GuiEdit.au3> #include <GDIPlus.au3> If Not _CheckDependencies() Then Exit ; can't run without dependencies. Global $bDropped, $sFile, $bDropAllowed = True ; create a blank file, or empty it if it's already created Global $hTail, $sLogFile = FileGetShortName(@ScriptDir & "\LogFile.txt") _GDIPlus_Startup() ; just for image format conversion to PNG (if needed) $Form1 = GUICreate("TSP art generator", 500, 650, -1, -1, -1, $WS_EX_ACCEPTFILES) ; --- options $Combo1 = GUICtrlCreateCombo("", 350, 505, 60, 25) GUICtrlCreateLabel("Sampling points", 415, 510, 80, 25) GUICtrlSetData($Combo1, "1000|2000|4000|6000|8000|10000|20000|40000|60000", "4000") ; some sampling rate $Checkbox1 = GUICtrlCreateCheckbox("Variable thickness line", 350, 535, 145, 25) $Checkbox2 = GUICtrlCreateCheckbox("Color (voronoi only)", 350, 565, 145, 25) ; --- Log viewer Global $hLog = GUICtrlCreateEdit("", 5, 500, 340, 145, BitOR($WS_VSCROLL, $WS_HSCROLL, $ES_AUTOVSCROLL, $ES_AUTOHSCROLL, $ES_MULTILINE, $ES_READONLY)) ; log viewer GUICtrlSetBkColor(-1, 0x000000) GUICtrlSetColor(-1, 0x00FF00) GUICtrlSetFont(-1, 9, -1, -1, "Courier New") ; following is a transparent control over the browser control ; purpose is to avoid that the drop event is captured by the browser control $hGlass = GUICtrlCreateLabel("", 0, 0, 500, 650) GUICtrlSetBkColor(-1, $GUI_BKCOLOR_TRANSPARENT) ; This is like a glass over the following underlying browser Control GUICtrlSetCursor(-1, 2) ; Cursor is an arrow (instead of the default I-beam) ; --- Embed a browser control Global $oIE = ObjCreate("Shell.Explorer.2") $hIE = GUICtrlCreateObj($oIE, 5, 5, 490, 490) $oIE.navigate("about:blank") AutoItSetOption("GUIOnEventMode", 1) GUISetOnEvent($GUI_EVENT_CLOSE, "_Exit") GUIRegisterMsg($WM_DROPFILES, "WM_DROPFILES") GUISetState(@SW_SHOW, $Form1) _LogPrint(@CRLF & _ "Hello," & @CRLF & _ "Drag and dropping images here above," & @CRLF & _ "will be converted into a TSP Art." & @CRLF & _ "have fun...") ; --- Main loop While 1 $nMsg = GUIGetMsg() Select Case $nMsg = $GUI_EVENT_CLOSE _Exit() Case $bDropped = True $bDropped = False $bDropAllowed = False ; Drop not allowed while generating _Generate_PST_Art() $bDropAllowed = True EndSelect WEnd ; --- Call externa programs the right sequence Func _Generate_PST_Art() _EmptyLog() ; empty the temporary log file _checkFileFormat($sFile) ; if dropped image isn't a PNG convert it to PNG _ShowInBrowser($sFile) ; show dropped image in the browser control ; step 1) Transform PNG image into a voronoi svg image ; ============================================================================ If GUICtrlRead($Checkbox1) = $GUI_CHECKED Then ; variable thickness line? $sOptions = "" Else $sOptions = " -f " ; fixed radus EndIf If GUICtrlRead($Checkbox2) = $GUI_CHECKED Then ; color points for voronoi? $sOptions = " -c " & $sOptions EndIf ; _call_External_Program(".\voronoi.exe " & $sOptions & "-s " & GUICtrlRead($Combo1) & " -n -I " & $sFile & " -O out.svg", True) _call_External_Program(FileGetShortName(@ScriptDir & '\voronoi.exe') & $sOptions & ' -s ' & GUICtrlRead($Combo1) & ' -n -I ' & $sFile & ' -O out.svg', True) _ShowInBrowser(FileGetShortName(@ScriptDir & "\out.svg")) ; show generated voronoi image in the browser control ; ; step 2) Extract points from the voronoi svg image and save to positions.tsp file ; for later input by the concorde TSP solver ; ============================================================================ _call_External_Program(FileGetShortName(@ScriptDir & '\svg_extract.exe') & " out.svg") _LogPrint("... going to next step ...") ; ; step 3) Resolve the Traveling Salesman Problem using the very good ; concorde.exe program (it needs the presence of the cygwin1.dll to work) ; ============================================================================ _call_External_Program(FileGetShortName(@ScriptDir & "\concorde.exe") & " -V -o tour.cyc positions.tsp", True) _LogPrint("... going to next step ...") ; ; step 3a) some adjustments to the tour.cyc file generated by concorde.exe ; ============================================================================ $hfile = FileOpen(FileGetShortName(@ScriptDir & '\tour.cyc')) Local $sContent = FileRead($hfile) FileClose($hfile) FileDelete(FileGetShortName(@ScriptDir & '\tour.cyc')) $sContent = StringReplace($sContent, Chr(0x20), Chr(0x0A)) _LogPrint("Replaced 0x20 with 0x0A " & @extended & " times.") $sContent = StringReplace($sContent, Chr(0x0A) & Chr(0x0A), Chr(0x0A)) _LogPrint("Replaced 0x0A 0x0A with 0x0A " & @extended & " times." & @CRLF) Local $x = StringInStr($sContent, Chr(0x0A)) ; first 0A $sContent = StringMid($sContent, $x + 1) ; remove first data (it's the number of points, not a point) $hfile = FileOpen(FileGetShortName(@ScriptDir & '\tour.cyc'), $FO_OVERWRITE + $FO_BINARY) FileWrite($hfile, $sContent) ; save adjusted data FileFlush($hfile) FileClose($hfile) ; ; step 4) "merge" data from out.svg and tour.cyc into the final tsp_art.svg file ; ============================================================================ If GUICtrlRead($Checkbox1) = $GUI_CHECKED Then $sOptions = " +w" ; variable thickness line Else $sOptions = "" ; fixed thickness line EndIf $sOptions = FileGetShortName(@ScriptDir & "\tsp2svg.exe") & " out.svg tour.cyc" & $sOptions _call_External_Program($sOptions) _ShowInBrowser(FileGetShortName(@ScriptDir & "\tsp_art.svg")) _LogPrint(@CRLF & _ "+-----------------------------------+" & @CRLF & _ "| End of conversion --> tsp_art.svg |" & @CRLF & _ "+-----------------------------------+" & @CRLF) EndFunc ;==>_Generate_PST_Art ; === Functions Func _call_External_Program($sCommand, $bVerbose = False) Local $sLine If $bVerbose = True Then $sCommand = @ComSpec & " /c " & $sCommand & ">>" & $sLogFile & " 2>>&1" EndIf Local $hPid = Run($sCommand, ".", @SW_HIDE) If Not $hPid Then _LogPrint("Error on run external program" & @CRLF) Return SetError(1) EndIf Do If $bVerbose Then $sLine = FileReadLine($hTail) If Not @error Then _LogPrint($sLine) EndIf EndIf Until Not ProcessExists($hPid) If $bVerbose Then $sLine = "..." ; "Task execution terminated ...." Do _LogPrint($sLine) $sLine = FileReadLine($hTail) Until @error EndIf EndFunc ;==>_call_External_Program Func _LogPrint($sLine) If StringLen(GUICtrlRead($hLog)) > 25000 Then ; Max Len of a CtrlBox is 30000 char _GUICtrlEdit_SetText($hLog, StringRight(GUICtrlRead($hLog), 20000)) ; short the content of CtrlBox to 20000 char EndIf _GUICtrlEdit_AppendText($hLog, $sLine & @CRLF) EndFunc ;==>_LogPrint Func WM_DROPFILES($hWnd, $iMsg, $wParam, $lParam) If $bDropAllowed Then Local $sExt = ".bmp|.png|.jpg|.gif" ; img drop filtering thanks to @UEZ Local $aFileList = _WinAPI_DragQueryFileEx($wParam) If Not @error Then For $i = 1 To $aFileList[0] If StringInStr($sExt, StringRegExpReplace($aFileList[$i], ".*(\.+)", "$1")) Then $bDropped = True $sFile = FileGetShortName($aFileList[$i]) ExitLoop EndIf Next Else _LogPrint("Error on drop" & @CRLF) EndIf _WinAPI_DragFinish($wParam) _LogPrint("Droped: " & $sFile & @CRLF) Return 0 EndIf EndFunc ;==>WM_DROPFILES Func _ShowInBrowser($sImg) ; setup Javascript engine with also embeded the "entity" library If StringRight($sImg, 3) = "svg" Then Else EndIf ; *** create a minimal 'html' page listing for the browser control Local $sHTML = "<HTML><HEAD>" & @CRLF & _ "<meta http-equiv=""X-UA-Compatible"" content=""IE=edge"" />" & @CRLF & _ "</HEAD>" & @CRLF & _ "<body>" & @CRLF & _ '<img src="' & $sImg & '" style="width:100%; height:100%;" />' & @CRLF & _ "</body>" & @CRLF & _ "</HTML>" & @CRLF ; html closing tags ; *** end of html page listing ; _LogPrint(">_" & @CRLF) $oIE.navigate('about:blank') While Not String($oIE.readyState) = 'complete' ; wait for about:blank Sleep(100) WEnd $oIE.document.Write($sHTML) ; inject lising directly to the HTML document: $oIE.document.close() ; close the write stream Sleep(1000) $oIE.document.execCommand("Refresh") EndFunc ;==>_ShowInBrowser Func _checkFileFormat($sFile) Local $hImage = _GDIPlus_ImageLoadFromFile($sFile) Local $aFormat = _GDIPlus_ImageGetRawFormat($hImage) If $aFormat[1] <> "PNG" Then _ConvertToPNG($hImage) _GDIPlus_ImageDispose($hImage) EndFunc ;==>_checkFileFormat Func _ConvertToPNG(ByRef $hImage) Local $CLSID = _GDIPlus_EncodersGetCLSID('PNG') $sFile = FileGetShortName(@ScriptDir & "\Input.png") _GDIPlus_ImageSaveToFileEx($hImage, $sFile, $CLSID) EndFunc ;==>_ConvertToPNG Func _EmptyLog() FileClose($hTail) $hTail = FileOpen($sLogFile, $FO_OVERWRITE) FileWrite($hTail, "Start log: " & @YEAR & '/' & @MON & '/' & @MDAY & ' ' & @HOUR & ':' & @MIN & ':' & @SEC & @CRLF) FileFlush($hTail) FileClose($hTail) $hTail = FileOpen($sLogFile) ; read only EndFunc ;==>_EmptyLog Func _CheckDependencies() Local $iDependencie = 0 $iDependencie += FileExists(@ScriptDir & "\voronoi.exe") ; http://www.drububu.com/illustration/tsp/voronoi.zip $iDependencie += FileExists(@ScriptDir & "\stippler.dll") ; " also contained in the above archive $iDependencie += FileExists(@ScriptDir & "\concorde.exe") ; http://www.math.uwaterloo.ca/tsp/concorde/downloads/codes/cygwin/concorde.exe.gz $iDependencie += FileExists(@ScriptDir & "\cygwin1.dll") ; get one from here https://cygwin.com/snapshots/ get cygwin1-xxxxxxxxx.dll.xz $iDependencie += FileExists(@ScriptDir & "\svg_extract.exe") ; http://www.drububu.com/illustration/tsp/svg_extract.zip $iDependencie += FileExists(@ScriptDir & "\tsp2svg.exe") ; http://www.drububu.com/illustration/tsp/tsp2svg.zip Return $iDependencie = 6 EndFunc ;==>_CheckDependencies Func _Exit() _GDIPlus_Shutdown() FileClose($hTail) AutoItSetOption("GUIOnEventMode", 0) GUIRegisterMsg($WM_DROPFILES, "") Exit EndFunc ;==>_Exit  

Here some graphical examples written completely in FreeBasic just for fun.  
_WinAPI_SetWindowTitleIcon Check for Numeric Entry in an EditBox using RegEx CreateWindowEx (hGUI) Example FB 3D Starfield Rotating Flight FB File2Bas Code Generator FB Fire Particles FB Fireworks FB GFX Examples FB Image to Trapezoid Transformation FB Layered Parallax Effect FB Plasma FB Puristic Clock FB Rotating Cube FB Rotating Earth FB Rutt Etra Izer Effect FB Simple Recursive Tree Generator FB Snowfall FB Tunnel Flight FB Water Effect FMOD Examples GDI - GDI+ 3D Sinus Wave GDI - GDI+ Animated Pythagoras Tree GDI - GDI+ Bezier Lines GDI - GDI+ Particles - Repulsive Force Sim v2.0 GDI - GDI+ Plasma v5 Booster GDI - GDI+ Random Pattern GDI - GDI+ Space Flight GDI - GDI+ Tunnel Flight - WipeOut Style GDI Classic Raytraced Tunnel GDI Elastic Twister Effect GDI Exploding Pixels GDI Infinite Image Zoom Flight GDI Liquid Pixels GDI Mandelbrot GDI Particle Repulsion Grid GDI Particles Mouse Attraction GDI Starfield GDI The Nautilus Raymarcher GDI Worm Tunnel Flight GDI+ 3D Starfield Scrolling v1 Booster GDI+ 3D Starfield Scrolling v3 Booster GDI+ Convert Bitmap to ASCII GDI+ GIF Anim to ASCII Player GDI+ Image Painting GDI+ Impossible Possible GDI+ Kaleidoscope GDI+ Performance Test - Au3 vs FB GDI+ Polar Clock GDI+ Rotating Earth GDI+ Spiral Text GDI+ Star Wars Scroller GDI+ Streamer GDI+ Swiss Railway Clock GDI+ The MATRIX Ini Read - Write Rutt_Etra_Izer_Booster Stack TitchySID uFMOD  
Download: FreeBasic Examples build 2019-05-08.rar
 
I will add new examples from time to time.
 
FreeBasic source codes are also included.
 

(Edited from original.  Please note that I AM NOT AN AUTOIT EXPERT.  I write code using Autoit frequently but I am no expert, especially when it comes to I/O.  So any remarks that start with "Why did you..." can be answered by referring to the first sentence.  This project was done in Autoit because of an interface I built to display the data.)
Attached is a program and ascii input file I wrote to read stock price data, convert it to binary and then read it back into the program in binary.  The goal was to show increased performance for reading the files in binary and provide a demo on how to read/write binary for int32, int64, double and strings for anyone who might find it helpful.  The results on my PC show the following:
Time to read ascii file only: 456.981951167202
Ascii read & process time: 6061.83075631701
Binary write file time: 14787.9184635239
Time just to read binary file: 42.418867292311
Binary read and process time: 4515.16129830537
A couple things to note:
1) The 32 MB ascii file took 10x longer to read than the 15 MB binary file.  Not entirely sure why.  Both were read into a buffer.
2) The Binary write takes a long time but I made no effort to optimize this because the plan was to write this file one time only so I don't mind if it takes longer to write this file.  I care much more about how long it takes to read the file because I will be reading it many times.
3) There was a modest gain in converting the ascii file to binary in terms of file size and reading speed.
So big picture... not sure it's worth the effort to convert the files to binary even though most of the data is numerical data in the binary file.  That was actually surprising as I expected there would be more of a difference.  Any ideas on how to get the binary data to read at a faster rate would be great.
 
binary.au3
2019_02_08.zip

hello Im wondering if it is possible to process image in autoit like this
1. firstly there is colorfull wallpaper
2. Fill all colors (exception rose color) - with white
3. Fill rose color with black color
I see Gdi functions have things to manipulate images
https://imgur.com/a/lFdY26g

Here another example to mark the desktop to get the marked region for capturing. This example is not perfect and not very fast (room for improvements).
;coded by UEZ build 2018-11-30 beta ;code cleanup up mLipok #include <APISysConstants.au3> #include <Array.au3> #include <GDIPlus.au3> #include <GUIConstantsEx.au3> #include <WinAPIGdi.au3> #include <WinAPISysWin.au3> #include <WindowsConstants.au3> Global $__g_hGUI_MarkArea, $__g_hGUI_Bg, $__g_iLabel_TL, $__g_iLabel_TM, $__g_iLabel_TR, $__g_iLabel_LM, $__g_iLabel_RM, $__g_iLabel_BL, $__g_iLabel_BM, _ $__g_iLabel_BR, $__g_iOldCursor, $__g_iW, $__g_iH, $__g_iColor_ResizeDots = 0xFFFFFF, $__g_iBorder = 4, $__g_bSelectionDone = False Global $aRect = _GDIPlus_MarkScreenRegionAnimated() _ArrayDisplay($aRect, "Marked area coordinates") Func _GDIPlus_MarkScreenRegionAnimated($bAnim = True) _GDIPlus_Startup() Local Const $hFullScreen = WinGetHandle("[TITLE:Program Manager;CLASS:Progman]") Local Const $aFullScreen = WinGetPos($hFullScreen) $__g_hGUI_Bg = GUICreate("", $aFullScreen[2], $aFullScreen[3], $aFullScreen[0], $aFullScreen[1], BitOR($WS_CLIPCHILDREN, $WS_POPUP), $WS_EX_TOPMOST) ;to avoid cursor flickering and for proper control read WinSetTrans($__g_hGUI_Bg, "", 0x01) $__g_hGUI_MarkArea = GUICreate("", 1, 1, -1, -1, $bAnim ? $WS_POPUP : BitOR($WS_POPUP, $WS_BORDER), BitOR($WS_EX_TOPMOST, $WS_EX_LAYERED), $__g_hGUI_Bg) GUISetBkColor(0xABCDEF, $__g_hGUI_MarkArea) If Not $bAnim Then $__g_iColor_ResizeDots = 0xFF0000 $__g_iLabel_TL = GUICtrlCreateLabel("", 0, 0, $__g_iBorder, $__g_iBorder) ;top left GUICtrlSetResizing(-1, $GUI_DOCKSIZE) GUICtrlSetBkColor(-1, $__g_iColor_ResizeDots) $__g_iLabel_TM = GUICtrlCreateLabel("", 0, 0, $__g_iBorder, $__g_iBorder) ;top mid GUICtrlSetResizing(-1, $GUI_DOCKSIZE) GUICtrlSetBkColor(-1, $__g_iColor_ResizeDots) $__g_iLabel_TR = GUICtrlCreateLabel("", 0, 0, $__g_iBorder, $__g_iBorder) ;top right GUICtrlSetResizing(-1, $GUI_DOCKSIZE) GUICtrlSetBkColor(-1, $__g_iColor_ResizeDots) $__g_iLabel_LM = GUICtrlCreateLabel("", 0, 0, $__g_iBorder, $__g_iBorder) ;left mid GUICtrlSetResizing(-1, $GUI_DOCKSIZE) GUICtrlSetBkColor(-1, $__g_iColor_ResizeDots) $__g_iLabel_RM = GUICtrlCreateLabel("", 0, 0, $__g_iBorder, $__g_iBorder) ;right mid GUICtrlSetResizing(-1, $GUI_DOCKSIZE) GUICtrlSetBkColor(-1, $__g_iColor_ResizeDots) $__g_iLabel_BL = GUICtrlCreateLabel("", 0, 0, $__g_iBorder, $__g_iBorder) ;bottom left GUICtrlSetResizing(-1, $GUI_DOCKSIZE) GUICtrlSetBkColor(-1, $__g_iColor_ResizeDots) $__g_iLabel_BM = GUICtrlCreateLabel("", 0, 0, $__g_iBorder, $__g_iBorder) ;bottom mid GUICtrlSetResizing(-1, $GUI_DOCKSIZE) GUICtrlSetBkColor(-1, $__g_iColor_ResizeDots) $__g_iLabel_BR = GUICtrlCreateLabel("", 0, 0, $__g_iBorder, $__g_iBorder) ;bottom right GUICtrlSetResizing(-1, $GUI_DOCKSIZE) GUICtrlSetBkColor(-1, $__g_iColor_ResizeDots) GUISetState(@SW_SHOWNA, $__g_hGUI_Bg) GUISetState(@SW_SHOW, $__g_hGUI_MarkArea) $__g_iOldCursor = MouseGetCursor() GUISetCursor(3, 1, $__g_hGUI_Bg) GUISetCursor(3, 1, $__g_hGUI_MarkArea) _WinAPI_SetLayeredWindowAttributes($__g_hGUI_MarkArea, 0xABCDEF, 0xF0) Local $aMPos, $aPrevMPos[2] = [MouseGetPos(0) + 1, MouseGetPos(1) + 1], $iID, $aCI, $iX, $iY, $aOldWinPos, $aOldMPos, $bMoved Local $aGUIStartPos, $iKey_Exit = GUICtrlCreateButton("", $aFullScreen[0] - 10, $aFullScreen[1] - 10, 1, 1), $aAccelKeys[1][2] = [["{ENTER}", $iKey_Exit]] GUISetAccelerators($aAccelKeys, $__g_hGUI_Bg) GUISetAccelerators($aAccelKeys, $__g_hGUI_MarkArea) #forceref $bMoved Do Switch GUIGetMsg() Case $GUI_EVENT_CLOSE, $iKey_Exit If $bAnim Then GUIRegisterMsg($WM_TIMER, "") DllCall("user32.dll", "bool", "KillTimer", "hwnd", $__g_hGUI_MarkArea, "uint_ptr", $iID) GUIRegisterMsg($WM_ERASEBKGND, "") EndIf _GDIPlus_Shutdown() Local $aResult = WinGetPos($__g_hGUI_MarkArea) $aResult[2] = WinGetClientSize($__g_hGUI_MarkArea)[0] $aResult[3] = WinGetClientSize($__g_hGUI_MarkArea)[1] GUIDelete($__g_hGUI_MarkArea) GUIDelete($__g_hGUI_Bg) If Not $__g_bSelectionDone Then $aResult = 0 Return $aResult EndSwitch $aMPos = MouseGetPos() If ($aMPos[0] <> $aPrevMPos[0] Or $aMPos[1] <> $aPrevMPos[1]) And (Not $__g_bSelectionDone) Then WinMove($__g_hGUI_MarkArea, "", $aMPos[0], $aMPos[1]) $aPrevMPos = $aMPos EndIf $aCI = GUIGetCursorInfo($__g_hGUI_MarkArea) If $aCI[2] And (Not $__g_bSelectionDone) Then $aGUIStartPos = WinGetPos($__g_hGUI_MarkArea) If $bAnim Then GUIRegisterMsg($WM_ERASEBKGND, "WM_ERASEBKGND") GUIRegisterMsg($WM_TIMER, "PlayBorderAnim") $iID = DllCall("User32.dll", "uint_ptr", "SetTimer", "hwnd", $__g_hGUI_MarkArea, "uint_ptr", 1, "uint", 50, "ptr", 0)[0] EndIf While $aCI[2] * Sleep(10) $aCI = GUIGetCursorInfo($__g_hGUI_MarkArea) $aMPos = MouseGetPos() $__g_iW = Abs($aMPos[0] - $aGUIStartPos[0]) + 1 $__g_iH = Abs($aMPos[1] - $aGUIStartPos[1]) + 1 If $aMPos[0] < $aGUIStartPos[0] Then $iX = $aMPos[0] Else $iX = $aGUIStartPos[0] EndIf If $aMPos[1] < $aGUIStartPos[1] Then $iY = $aMPos[1] Else $iY = $aGUIStartPos[1] EndIf WinMove($__g_hGUI_MarkArea, "", $iX, $iY, $__g_iW, $__g_iH) UpdateCtrlPos($bAnim) WEnd $__g_bSelectionDone = True GUISetCursor(3, 1, $__g_hGUI_MarkArea) ElseIf $aCI[3] And $__g_bSelectionDone Then $aGUIStartPos = WinGetPos($__g_hGUI_MarkArea) If _WinAPI_PtInRectEx(MouseGetPos(0), MouseGetPos(1), $aGUIStartPos[0], $aGUIStartPos[1], $aGUIStartPos[0] + $aGUIStartPos[2], $aGUIStartPos[1] + $aGUIStartPos[3]) Then $aMPos = MouseGetPos() $aGUIStartPos = WinGetPos($__g_hGUI_MarkArea) While $aCI[3] * Sleep(10) $aCI = GUIGetCursorInfo($__g_hGUI_MarkArea) WinMove($__g_hGUI_MarkArea, "", $aGUIStartPos[0] - ($aMPos[0] - MouseGetPos(0)), $aGUIStartPos[1] - ($aMPos[1] - MouseGetPos(1)), $__g_iW, $__g_iH) GUISetCursor(0, 1, $__g_hGUI_Bg) GUISetCursor(0, 1, $__g_hGUI_MarkArea) WEnd GUISetCursor(3, 1, $__g_hGUI_Bg) GUISetCursor(3, 1, $__g_hGUI_MarkArea) EndIf EndIf If $__g_bSelectionDone Then $aCI = GUIGetCursorInfo($__g_hGUI_MarkArea) If @error Then ContinueLoop Switch $aCI[4] Case $__g_iLabel_TL GUISetCursor(12, 1, $__g_hGUI_MarkArea) If $aCI[2] Then $aOldWinPos = WinGetPos($__g_hGUI_MarkArea) $aOldMPos = MouseGetPos() While $aCI[2] * Sleep(10) $aCI = GUIGetCursorInfo($__g_hGUI_MarkArea) WinMove($__g_hGUI_MarkArea, "", MouseGetPos(0), MouseGetPos(1), $aOldWinPos[2] + ($aOldMPos[0] - MouseGetPos(0)), $aOldWinPos[3] + ($aOldMPos[1] - MouseGetPos(1))) WEnd UpdateCtrlPos($bAnim) EndIf Case $__g_iLabel_BR GUISetCursor(12, 1, $__g_hGUI_MarkArea) If $aCI[2] Then $aOldWinPos = WinGetPos($__g_hGUI_MarkArea) $aOldMPos = MouseGetPos() While $aCI[2] * Sleep(10) $aCI = GUIGetCursorInfo($__g_hGUI_MarkArea) WinMove($__g_hGUI_MarkArea, "", $aOldWinPos[0], $aOldWinPos[1], $aOldWinPos[2] - ($aOldMPos[0] - MouseGetPos(0)), $aOldWinPos[3] - ($aOldMPos[1] - MouseGetPos(1))) WEnd UpdateCtrlPos($bAnim) EndIf Case $__g_iLabel_TR GUISetCursor(10, 1, $__g_hGUI_MarkArea) If $aCI[2] Then $aOldWinPos = WinGetPos($__g_hGUI_MarkArea) $aOldMPos = MouseGetPos() While $aCI[2] * Sleep(10) $aCI = GUIGetCursorInfo($__g_hGUI_MarkArea) WinMove($__g_hGUI_MarkArea, "", $aOldWinPos[0], MouseGetPos(1), $aOldWinPos[2] - ($aOldMPos[0] - MouseGetPos(0)), $aOldWinPos[3] + ($aOldMPos[1] - MouseGetPos(1))) WEnd UpdateCtrlPos($bAnim) EndIf Case $__g_iLabel_BL GUISetCursor(10, 1, $__g_hGUI_MarkArea) If $aCI[2] Then $aOldWinPos = WinGetPos($__g_hGUI_MarkArea) $aOldMPos = MouseGetPos() While $aCI[2] * Sleep(10) $aCI = GUIGetCursorInfo($__g_hGUI_MarkArea) WinMove($__g_hGUI_MarkArea, "", MouseGetPos(0), $aOldWinPos[1], $aOldWinPos[2] + ($aOldMPos[0] - MouseGetPos(0)), $aOldWinPos[3] - ($aOldMPos[1] - MouseGetPos(1))) WEnd UpdateCtrlPos($bAnim) EndIf Case $__g_iLabel_LM GUISetCursor(13, 1, $__g_hGUI_MarkArea) If $aCI[2] Then $aOldWinPos = WinGetPos($__g_hGUI_MarkArea) $aOldMPos = MouseGetPos() While $aCI[2] * Sleep(10) $aCI = GUIGetCursorInfo($__g_hGUI_MarkArea) WinMove($__g_hGUI_MarkArea, "", MouseGetPos(0), $aOldWinPos[1], $aOldWinPos[2] + ($aOldMPos[0] - MouseGetPos(0)), $aOldWinPos[3]) WEnd UpdateCtrlPos($bAnim) EndIf Case $__g_iLabel_RM GUISetCursor(13, 1, $__g_hGUI_MarkArea) If $aCI[2] Then $aOldWinPos = WinGetPos($__g_hGUI_MarkArea) $aOldMPos = MouseGetPos() While $aCI[2] * Sleep(10) $aCI = GUIGetCursorInfo($__g_hGUI_MarkArea) WinMove($__g_hGUI_MarkArea, "", $aOldWinPos[0], $aOldWinPos[1], $aOldWinPos[2] - ($aOldMPos[0] - MouseGetPos(0)), $aOldWinPos[3]) WEnd UpdateCtrlPos($bAnim) EndIf Case $__g_iLabel_TM GUISetCursor(11, 1, $__g_hGUI_MarkArea) If $aCI[2] Then $aOldWinPos = WinGetPos($__g_hGUI_MarkArea) $aOldMPos = MouseGetPos() While $aCI[2] * Sleep(10) $aCI = GUIGetCursorInfo($__g_hGUI_MarkArea) WinMove($__g_hGUI_MarkArea, "", $aOldWinPos[0], MouseGetPos(1), $aOldWinPos[2], $aOldWinPos[3] + ($aOldMPos[1] - MouseGetPos(1))) WEnd UpdateCtrlPos($bAnim) EndIf Case $__g_iLabel_BM GUISetCursor(11, 1, $__g_hGUI_MarkArea) If $aCI[2] Then $aOldWinPos = WinGetPos($__g_hGUI_MarkArea) $aOldMPos = MouseGetPos() While $aCI[2] * Sleep(10) $aCI = GUIGetCursorInfo($__g_hGUI_MarkArea) WinMove($__g_hGUI_MarkArea, "", $aOldWinPos[0], $aOldWinPos[1], $aOldWinPos[2], $aOldWinPos[3] - ($aOldMPos[1] - MouseGetPos(1))) WEnd UpdateCtrlPos($bAnim) EndIf Case Else GUISetCursor(3, 1, $__g_hGUI_MarkArea) EndSwitch EndIf Until False EndFunc ;==>_GDIPlus_MarkScreenRegionAnimated Func UpdateCtrlPos($bAnim = True) Local Const $aGUIStartPos = WinGetPos($__g_hGUI_MarkArea) If $__g_bSelectionDone And $bAnim Then GUIRegisterMsg($WM_TIMER, "") $__g_iW = $aGUIStartPos[2] $__g_iH = $aGUIStartPos[3] ControlMove($__g_hGUI_MarkArea, "", $__g_iLabel_TL, 0, 0, $__g_iBorder, $__g_iBorder) ControlMove($__g_hGUI_MarkArea, "", $__g_iLabel_TM, ($__g_iW - $__g_iBorder) / 2, 0, $__g_iBorder, $__g_iBorder) ControlMove($__g_hGUI_MarkArea, "", $__g_iLabel_TR, ($__g_iW - $__g_iBorder - $__g_iBorder / 2), 0, $__g_iBorder, $__g_iBorder) ControlMove($__g_hGUI_MarkArea, "", $__g_iLabel_LM, 0, ($__g_iH - $__g_iBorder) / 2, $__g_iBorder, $__g_iBorder) ControlMove($__g_hGUI_MarkArea, "", $__g_iLabel_RM, ($__g_iW - $__g_iBorder - $__g_iBorder / 2), ($__g_iH - $__g_iBorder) / 2, $__g_iBorder, $__g_iBorder) ControlMove($__g_hGUI_MarkArea, "", $__g_iLabel_BL, 0, ($__g_iH - $__g_iBorder - $__g_iBorder / 2), $__g_iBorder, $__g_iBorder) ControlMove($__g_hGUI_MarkArea, "", $__g_iLabel_BM, ($__g_iW - $__g_iBorder) / 2, ($__g_iH - $__g_iBorder - $__g_iBorder / 2), $__g_iBorder, $__g_iBorder) ControlMove($__g_hGUI_MarkArea, "", $__g_iLabel_BR, ($__g_iW - $__g_iBorder - $__g_iBorder / 2), ($__g_iH - $__g_iBorder - $__g_iBorder / 2), $__g_iBorder, $__g_iBorder) If $__g_bSelectionDone And $bAnim Then GUIRegisterMsg($WM_TIMER, "PlayBorderAnim") EndFunc ;==>UpdateCtrlPos Func PlayBorderAnim() Local $aWinPos = WinGetClientSize($__g_hGUI_MarkArea), $iW = $aWinPos[0], $iH = $aWinPos[1] Local Static $fOffset = 0 Local Const $iSize = $__g_iBorder / 2 Local Const $hDC = _WinAPI_GetDC($__g_hGUI_MarkArea) Local Const $hHBitmap = _WinAPI_CreateCompatibleBitmap($hDC, $iW, $iH) Local Const $hDC_backbuffer = _WinAPI_CreateCompatibleDC($hDC) Local Const $DC_obj = _WinAPI_SelectObject($hDC_backbuffer, $hHBitmap) Local Const $hCanvas = _GDIPlus_GraphicsCreateFromHDC($hDC_backbuffer) Local Const $hPen = _GDIPlus_PenCreate(0xFF0178D7, $iSize), $hPen2 = _GDIPlus_PenCreate(0xFFFFFFFF, $iSize), _ $hBrush = _GDIPlus_BrushCreateSolid(0xFF000000 + $__g_iColor_ResizeDots), $hPen3 = _GDIPlus_PenCreate(0xFF000000) _GDIPlus_PenSetDashStyle($hPen, $GDIP_DASHSTYLEDASHDOT) _GDIPlus_GraphicsClear($hCanvas, 0xFFABCDEF) ;for faster performance direct dll calls DllCall($__g_hGDIPDll, "int", "GdipDrawRectangle", "handle", $hCanvas, "handle", $hPen2, "float", 1 + $iSize, "float", 1 + $iSize, "float", $iW - 2 * $iSize - 2, "float", $iH - 2 * $iSize - 2) DllCall($__g_hGDIPDll, "int", "GdipSetPenDashOffset", "handle", $hPen, "float", $fOffset) DllCall($__g_hGDIPDll, "int", "GdipDrawRectangle", "handle", $hCanvas, "handle", $hPen, "float", 1 + $iSize, "float", 1 + $iSize, "float", $iW - 2 * $iSize - 2, "float", $iH - 2 * $iSize - 2) DllCall($__g_hGDIPDll, "int", "GdipFillRectangle", "handle", $hCanvas, "handle", $hBrush, "float", 0, "float", 0, "float", $__g_iBorder + 1, "float", $__g_iBorder + 1) DllCall($__g_hGDIPDll, "int", "GdipDrawRectangle", "handle", $hCanvas, "handle", $hPen3, "float", 0, "float", 0, "float", $__g_iBorder + 1, "float", $__g_iBorder + 1) DllCall($__g_hGDIPDll, "int", "GdipFillRectangle", "handle", $hCanvas, "handle", $hBrush, "float", ($iW - $__g_iBorder) / 2, "float", 0, "float", $__g_iBorder + 1, "float", $__g_iBorder + 1) DllCall($__g_hGDIPDll, "int", "GdipDrawRectangle", "handle", $hCanvas, "handle", $hPen3, "float", ($iW - $__g_iBorder) / 2, "float", 0, "float", $__g_iBorder + 1, "float", $__g_iBorder + 1) DllCall($__g_hGDIPDll, "int", "GdipFillRectangle", "handle", $hCanvas, "handle", $hBrush, "float", ($iW - $__g_iBorder) - 2, "float", 0, "float", $__g_iBorder + 1, "float", $__g_iBorder + 1) DllCall($__g_hGDIPDll, "int", "GdipDrawRectangle", "handle", $hCanvas, "handle", $hPen3, "float", ($iW - $__g_iBorder) - 2, "float", 0, "float", $__g_iBorder + 1, "float", $__g_iBorder + 1) DllCall($__g_hGDIPDll, "int", "GdipFillRectangle", "handle", $hCanvas, "handle", $hBrush, "float", 0, "float", ($iH - $__g_iBorder) / 2, "float", $__g_iBorder + 1, "float", $__g_iBorder + 1) DllCall($__g_hGDIPDll, "int", "GdipDrawRectangle", "handle", $hCanvas, "handle", $hPen3, "float", 0, "float", ($iH - $__g_iBorder) / 2, "float", $__g_iBorder + 1, "float", $__g_iBorder + 1) DllCall($__g_hGDIPDll, "int", "GdipFillRectangle", "handle", $hCanvas, "handle", $hBrush, "float", ($iW - $__g_iBorder) - 2, "float", ($iH - $__g_iBorder) / 2, "float", $__g_iBorder + 1, "float", $__g_iBorder + 1) DllCall($__g_hGDIPDll, "int", "GdipDrawRectangle", "handle", $hCanvas, "handle", $hPen3, "float", ($iW - $__g_iBorder) - 2, "float", ($iH - $__g_iBorder) / 2, "float", $__g_iBorder + 1, "float", $__g_iBorder + 1) DllCall($__g_hGDIPDll, "int", "GdipFillRectangle", "handle", $hCanvas, "handle", $hBrush, "float", 0, "float", ($iH - $__g_iBorder) - 2, "float", $__g_iBorder + 1, "float", $__g_iBorder + 1) DllCall($__g_hGDIPDll, "int", "GdipDrawRectangle", "handle", $hCanvas, "handle", $hPen3, "float", 0, "float", ($iH - $__g_iBorder) - 2, "float", $__g_iBorder + 1, "float", $__g_iBorder + 1) DllCall($__g_hGDIPDll, "int", "GdipFillRectangle", "handle", $hCanvas, "handle", $hBrush, "float", ($iW - $__g_iBorder) / 2, "float", ($iH - $__g_iBorder) - 2, "float", $__g_iBorder + 1, "float", $__g_iBorder + 1) DllCall($__g_hGDIPDll, "int", "GdipDrawRectangle", "handle", $hCanvas, "handle", $hPen3, "float", ($iW - $__g_iBorder) / 2, "float", ($iH - $__g_iBorder) - 2, "float", $__g_iBorder + 1, "float", $__g_iBorder + 1) DllCall($__g_hGDIPDll, "int", "GdipFillRectangle", "handle", $hCanvas, "handle", $hBrush, "float", ($iW - $__g_iBorder) - 2, "float", ($iH - $__g_iBorder) - 2, "float", $__g_iBorder + 1, "float", $__g_iBorder + 1) DllCall($__g_hGDIPDll, "int", "GdipDrawRectangle", "handle", $hCanvas, "handle", $hPen3, "float", ($iW - $__g_iBorder) - 2, "float", ($iH - $__g_iBorder) - 2, "float", $__g_iBorder + 1, "float", $__g_iBorder + 1) _WinAPI_BitBlt($hDC, 0, 0, $iW, $iH, $hDC_backbuffer, 0, 0, $SRCCOPY) $fOffset += 0.5 _GDIPlus_GraphicsDispose($hCanvas) _WinAPI_SelectObject($hDC_backbuffer, $DC_obj) _WinAPI_DeleteDC($hDC_backbuffer) _WinAPI_DeleteObject($hHBitmap) _WinAPI_ReleaseDC($__g_hGUI_MarkArea, $hDC) _GDIPlus_PenDispose($hPen) _GDIPlus_PenDispose($hPen2) _GDIPlus_PenDispose($hPen3) _GDIPlus_BrushDispose($hBrush) EndFunc ;==>PlayBorderAnim Func WM_ERASEBKGND($hWnd, $iMsgm, $wParam, $lParam) ;suppress repainting to avoid flickering but causes some other side effects #forceref $iMsgm, $wParam, $lParam, $hWnd Local Const $hBrush = _WinAPI_CreateSolidBrush(0xEFCDAB) ;BGR format ;~ _WinAPI_RedrawWindow($__g_hGUI_MarkArea, 0, 0, BitOR($RDW_NOERASE, $RDW_NOCHILDREN, $RDW_NOFRAME, $RDW_VALIDATE)) _WinAPI_SetClassLongEx($__g_hGUI_MarkArea, $GCL_HBRBACKGROUND, $hBrush) _WinAPI_DeleteObject($hBrush) Return 0 EndFunc ;==>WM_ERASEBKGND  
Just press the lmb and move your mouse. When lmb is released you can adjust the size of the window by dragging the white rectangle to any direction. Rmb will move the marked area.
Press ESC to get the coordinates of the marked region.
If you have any improvements, please post it here.
 
Tested on Win10 x64 only.