Mouseclick() works inconsistently?

[IAMK]

I have a script which I've been using for over a year, and now I'm seeing issues with it.
I originally attributed the issue to the system becoming laggy, so I added sleeps (even up to 1-second long, which is a long time). Hence, I don't believe the issue is lag. When I use my fingers for the touchscreen, or the mouse for manual click, it seem to work consistently.

Now, when I'm trying to debug the script, It runs the same line of code (it's the very first line of the script), but sometimes it clicks and sometimes it doesn't.
The code I'm having issues with is literally just MouseClick("primary", 50, 50, 1, 0) ;Close the video.

Note: I'm always running the script on the same program (which I am not restarting - but I have tried powercycling the system and it makes no difference), at the same screen, but the result is inconsistent.
Is there possibly some setting a computer/program can have which makes MouseClick() work inconsistantly, which I need to fix?

One thing I have tried is putting it in a loop. Then, when it doesn't work, it will keep pressing the same location every .5 seconds (but doesn't work).
I then use the touchscreen to touch another location, and after 1-5 attempts of the touch screen, the MouseClick() in the loop works (getting stuck later again until I use the touchscreen again).
Note: The movement of the mouse works 100% of the time. It's just the click that doesn't always work.

This is making my head explode.
Any help would be greatly appreciated.

Edited November 28, 2019 by IAMK

[JLogan3o13]

@IAMK How can we help you with your code when you don't post any?

[ozymandius257]

Have you tried using MouseClick("Left".....  ?

[IAMK]

The code is literally just:

Global $file = FileOpen("LogScript.txt", 1)

;SCRIPT============================================================================================
FileWrite($file, _Now() & ": AUTOIT - Started." & @CRLF)

MouseClick("primary", 50, 50, 1, 0) ;Makes sure the video is closed.
Sleep(500)

Upon disabling my ToolTip, which was on MouseGetPos(0), MouseGetPos(1) (separate script), this code worked fine.

It seems there is some race condition happening with a ToolTip on top of the cursor and performing a mouseclick.
Not sure why that would be the case though.